Whole body tracking of superparamagnetic iron oxide nanoparticle-labelled cells – a rheumatoid arthritis mouse model
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چکیده
منابع مشابه
Superparamagnetic iron oxide nanoparticle targeting of MSCs in vascular injury.
Vascular occlusion can result in fatal myocardial infarction, stroke or loss of limb in peripheral arterial disease. Interventional balloon angioplasty is a common first line procedure for vascular disease treatment, but long term success is limited by restenosis and neointimal hyperplasia. Cellular therapies have been proposed to mitigate these issues; however efficacy is low, in part due to p...
متن کاملIn Vivo MRI Tracking of Polyethylenimine-Wrapped Superparamagnetic Iron Oxide Nanoparticle–Labeled BMSCs for Cartilage Repair
OBJECTIVE To evaluate the feasibility of tracking polyethylenimine (PEI)-wrapped superparamagnetic iron oxide (SPIO) nanoparticle-labeled, bone marrow-derived mesenchymal stem cells (BMSCs) by in vivo magnetic resonance imaging (MRI) in articular cartilage repair in a minipig model. METHODS Eighteen Guizhou minipigs were randomly divided into three groups (groups A, B, and C). In group A, PEI...
متن کاملeffect of superparamagnetic iron oxide nanoparticles-labeling on mouse embryonic stem cells
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متن کاملSuperparamagnetic iron oxide nanoparticle targeting of adipose tissue-derived stem cells in diabetes-associated erectile dysfunction
Erectile dysfunction (ED) is a major complication of diabetes, and many diabetic men with ED are refractory to common ED therapies. Adipose tissue-derived stem cells (ADSCs) have been shown to improve erectile function in diabetic animal models. However, inadequate cell homing to damaged sites has limited their efficacy. Therefore, we explored the effect of ADSCs labeled with superparamagnetic ...
متن کاملMouse model of rheumatoid arthritis
Adipue and colleagues [1] have characterized the novel IIJ (inherited infl amed joints) mouse strain, a new murine model of infl ammatory, possibly autoimmune, arthritis that is similar both histologically and serologically to human rheumatoid arthritis (RA) and other murine models of autoimmune arthritis [1]. RA is a chronic and progressive infl ammatory disorder characterized by synovitis and...
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ژورنال
عنوان ژورنال: Stem Cell Research & Therapy
سال: 2013
ISSN: 1757-6512
DOI: 10.1186/scrt337